A Case of anti-Yo antibody positive subacute cerebellar degeneration presenting as acute cerebrovascular disease in an undiagnosed breast cancer patient

Zhang Sumei, Hao Xinxin and Chen Xuan (2022). A Case of anti-Yo antibody positive subacute cerebellar degeneration presenting as acute cerebrovascular disease in an undiagnosed breast cancer patient. Journal of Multiscale Neuroscience 1(2), 102-108

A 41-year-old female patient presented initially with right limb ataxia, which resembled the clinical process of acute cerebrovascular disease. However, no obvious acute infarction was found on Cranial MR2. The patient's symptoms did not significantly improve after treatment with antiplatelet aggregation, stabilizing plate, clearing oxygen free radicals, and improving circulation. The patient was later diagnosed with subacute cerebellar degeneration by detecting Paratumor-related antibodies in cerebrospinal fluid and blood. Further investigation by PET-CT scan of the whole body revealed a breast tumor.

Keywords: Acute cerebrovascular disease, Subacute cerebellar degeneration, Ataxia, Breast cancer.

Conflict of Interest

    The authors declare no conflict of interest

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